Element Plutonium (specifically the Pu-238 isotope) was isolated for the first time at Berkeley Radiation Laboratory at the University of California, Berkeley on 14th December 1940. The team of scientists who conducted the majority of the work consisted of Glenn T. Seaborg, Joseph W. Kennedy, Edwin M. McMillan and Arthur C. Wahl.
Plutonium was later produced at the Hanford Atomic Facility and was subsequently used in the Fat Man atomic bomb dropped over Nagasaki in Japan.